Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

Definition of Polyarteritis nodosa

Medically reviewed by Min Clinic Staff | Updated: January 2026

Polyarteritis nodosa: An autoimmune disease that is characterized by spontaneous inflammation of the arteries (arteritis) and can affect any organ of the body. Polyarteritis nodosa most commonly affects muscles, joints, intestines, nerves, kidneys, and skin. Inflammation of the arteries can lead to inadequate blood supply and permanent damage to organs. Typically, polyarteritis nodosa is treated with medications that suppress the immune system, such as prednisone and cyclophosphamide.