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Definition of Neo- (prefix)

Medically reviewed by Min Clinic Staff | Updated: January 2026

Neo- (prefix): Prefix meaning new. From the Greek "neos", new, young, fresh, recent.

Examples of terms starting with "neo-" include neonatal and neonate (the newborn), neoplasia and neoplasm (new growth = tumor), etc.

The opposite of neo- is paleo-. Although paleo- does enter occasionally into medical usage, it is far less commonly encountered than neo- in medicine (and on the pharmacy shelves where there is Neomycin but no Paleomycin).