Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Signature
Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026
Signature: That part of the prescription that contains the doctor's directions to the patient. For example, the signature might say "take twice daily with food". Also known as the sig..
The word "signature" comes from the Latin "signare" meaning "to sign or mark."