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Definition of Zygote

Medically reviewed by Min Clinic Staff | Updated: January 2026

Zygote: The cell formed by the union of a male sex cell (a sperm) and a female sex cell (an ovum). The zygote develops into the embryo following the instruction encoded in its genetic material, the DNA.

The unification of a sperm and an ovum to form a zygote constitutes fertilization.