Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

Definition of X (in genetics)

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

X (in genetics): Although the letter X can be used as a symbol in various ways (such as with X-rays, the X-axis of a graph, etc.), "the X " in genetics and medicine today usually refers to the X chromosome.

The X is the sex chromosome that is found twice in chromosomally normal females and singly along with a Y chromosome in chromosomally normal males. The complete chromosome complement consisting of 46 chromosomes including the two sex chromosomes is thus conventionally written as 46,XX for chromosomally normal females and 46,XY for chromosomally normal males.

Need Expert Advice on Your Condition?

Get a personalized video breakdown and treatment plan from our senior neurosurgeons using your MRI/CT scans.

👉 Request MRI Review