Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

Definition of Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

Sweet syndrome (acute febrile neutrophilic dermatosis): This rare skin condition develops after an infection, illness, or as a reaction to medications. Sweet syndrome can also occur as a reaction to certain cancers, and medical professionals do not know its exact cause. It causes the rapid onset of painful red bumps on the trunk, head, arms, legs, or neck. Other symptoms and signs can include fever, fatigue, headache, muscle pain, joint pain, and the presence of an elevated number of a white blood cells type (neutrophils). The red bumps can form painful patches. It is most common in women and in people aged 30-60.