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Definition of Transdifferentiation
Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026
Transdifferentiation: 1. The change of a cell or tissue from one differentiated state to another. 2. The differentiation of a tissue-specific stem cell into another type of cell as, for example, a bone marrow stem cell differentiating into a neuron.