Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Speckled iris
Medically reviewed by Min Clinic Staff | Updated: January 2026
Speckled iris: Due to little white (or lightly colored) spots that are slightly elevated on the surface of the iris. These spots, arranged in a ring concentric with the pupil, occur in normal children but are far more frequent in Down's syndrome (trisomy 21). They were described in 1924 by Thomas Brushfield, are called Brushfield's spots, and are due to aggregation of a normal iris element (connective tissue).