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Definition of THG

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

THG: Tetrahydrogestrinone. A "designer steroid." THG first surfaced in October 2003 with reports of its illicit use by athletes. A very potent androgenic steroid, with side effects such as hirsutism, acne and infertility. Considered a controlled substance in the United States. (CIII)