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Definition of Tetranucleotide

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

Tetranucleotide: A sequence of 4 base pairs. (Bases are the building blocks of DNA.) Expansion of a tetranucleotide repeat (CCTG) in the ZNF9 gene causes type 2 myotonic dystrophy.