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Definition of Reinstein syndrome
Medically reviewed by Min Clinic Staff | Updated: January 2026
Reinstein syndrome: A heritable syndrome characterized by eye disease (specifically, macular degeneration and inverse retinitis pigmentosa), progressive hearing loss, and hypogonadism. Inverse retinitis pigmentosa differs from the common form of retinitis pigmentosa in the absence of night blindness, early loss of central vision, and preference for dim illumination. The syndrome was first described in 1971 by Reinstein and Chalfin.