Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

Definition of Reading frame

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

Reading frame: One of the three possible ways to read a nucleotide sequence in DNA, depending on whether reading starts with the first, second, or third base in a triplet.