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Definition of Multiple subpial transection

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

Multiple subpial transection: A multiple subpial transection (MST) is a procedure is used to help control seizures that begin in areas of the brain that cannot be safely removed. The surgeon makes a series of shallow cuts (transections) in the brain tissue. These cuts interrupt the movement of seizure impulses but do not disturb normal brain activity, leaving the person's abilities intact.