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Definition of Peroxisome proliferator-activated receptor (PPAR)

Medically reviewed by Min Clinic Staff | Updated: January 2026

Peroxisome proliferator-activated receptor (PPAR): a type of nuclear hormone receptor within cells that ultimately affects gene expression. There are 3 types of PPARs: alpha, gamma, and beta/delta. These receptors play a major role in the maintenance of metabolism, cell differentiation, and inflammation.