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Definition of Mole
Medically reviewed by Min Clinic Staff | Updated: January 2026
Mole: 1. In dermatology a mole is a pigmented spot on the skin. The medical term for mole is melanocytic nevus (a nevus composed of melanocytes).
2. In gynecology, a mass within
the uterus formed of partly developed products of conception.
3. In biochemistry, the molecular weight of a substance. In more technical terms, a mole is the number of atoms in exactly 12 g of carbon-12. Mole in this sense is short for molecular weight.