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Definition of Percutaneous umbilical blood sampling (PUBS)
Medically reviewed by Min Clinic Staff | Updated: January 2026
Percutaneous umbilical blood sampling (PUBS): In percutaneous umbilical blood sampling , a needle is inserted through the mother's abdominal wall and uterine wall. Blood can be withdrawn from the umbilical vein at the point where the umbilical cord inserts (goes) into the placenta. Blood may also be taken from the umbilical vein on its way to the fetal liver. Percutaneous umbilical blood sampling is a technique used both for prenatal diagnosis and prenatal treatment of the fetus.