Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

Definition of Mitochondrial disease

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

Mitochondrial disease: A mutation in the mitochondrial chromosome that is responsible for a disease. Known mitochondrial diseases include the eye disease Leber hereditary optic atrophy; myoclonus epilepsy with ragged red fibers (MERRF); and mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS syndrome).

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