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Definition of Microchimerism

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

Microchimerism: The presence of two genetically distinct and separately derived populations of cells, one population being at a low concentration, in the same individual or an organ such as the bone marrow. Microchimerism may be due to transfer of cells between mother and fetus or between two twins. Other sources of microchimerism include blood transfusions and transplants. See also: Chimera.