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Definition of Noncoding DNA
Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026
Noncoding DNA: The strand of DNA that does not carry the information necessary to make proteins. DNA normally has two strands -- the coding strand and the non-coding strand. Although these strands are exact mirror images of one another, only the coding strand contains the information for making proteins. The non-coding strand does not.
Noncoding DNA is also known as the antisense strand.