Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

Definition of Nodes, Osler's

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

Nodes, Osler's: A diagnostic sign of bacterial infection of the heart (subacute bacterial endocarditis). These are small (the size of split peas), tender, transient nodules in the pads of fingers and toes and the palms and soles. Named for the Canadian-born physician Sir William Osler (1849-1919).