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Definition of Osteo- (prefix)

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

Osteo- (prefix): Combining form meaning bone. From the Greek "osteon", bone. Appears for instance in osteoarthritis, osteochondroma osteodystrophy, osteogenesis, osteomyelitis, osteopathy, osteopetrosis, osteoporosis, osteosarcoma, etc.