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Definition of Neurofibromatosis
Medically reviewed by Min Clinic Staff | Updated: January 2026
Neurofibromatosis: A genetic disorder of the nervous system that primarily affects the development and growth of neural (nerve) cell tissues, causes tumors to grow on nerves, and may produce other abnormalities. Neurofibromatosis consists of two very different disorders: neurofibromatosis type 1 (NF1) and neurofibromatosis type 2 (NF2).