Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Pachyderma
Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026
Pachyderma: Thick skin, like that of a pachyderm (an elephant, rhinoceros, or hippopotamus). The adjective is pachydermatous. Pachyderma can occur in several medical conditions, such as chronic lymphedema.
From the Greek pachydermos meaning "thick skin" from pachys meaning "thick" + derma meaning "skin."