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Definition of Lower GI series
Medically reviewed by Min Clinic Staff | Updated: January 2026
Lower GI series: Short for lower gastrointestinal series. A series of x-rays of the rectum, colon and lower section of the small intestine taken after the patient has a barium enema. Barium is a white, chalky substance that coats the organs so they will show up on the x-ray. Also called a barium enema or a barium enema x-ray.