Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

Definition of Upregulation

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

Upregulation: An increase in the number of receptors on the surface of target cells, making the cells more sensitive to a hormone or another agent. For example, there is an increase in uterine oxytocin receptors in the third trimester of pregnancy, promoting the contraction of the smooth muscle of the uterus.

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