Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

Definition of Leptomeningeal

Medically reviewed by Min Clinic Staff | Updated: January 2026

Leptomeningeal: Having to do with the leptomeninges, the two innermost layers of tissues that cover the brain and spinal cord. Leptomeningeal metastasis refers to cancer that has spread from the original (primary) tumor to the leptomeninges.