Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

Definition of Macule

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

Macule: A circumscribed change in the color of skin that is neither raised nor depressed. Macules are completely flat and can only be appreciated by visual inspection and not by touch. Physicians refer to flat skin spots on the skin as macules, as opposed to papules.