Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

Definition of Leiomyosarcoma

Medically reviewed by Min Clinic Staff | Updated: January 2026

Leiomyosarcoma: A malignant tumor that originates in smooth muscle, the major structural component of most hollow internal organs and the walls of blood vessels. Leiomyosarcoma can occur almost anywhere in the body but is most frequently found in the uterus and gastrointestinal tract. Complete surgical excision, if possible, is the treatment of choice.