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Definition of Involute
Medically reviewed by Min Clinic Staff | Updated: January 2026
Involute: 1. Literally, to turn inward or roll inward. 2. To decrease in size after an enlargement. The uterus involutes after pregnancy. The thymus involutes after adolescence. 3. To undergo a retrograde change. After treatment, a tumor may involute. 4. To shrink physically and emotionally with advancing age.
From the Latin involutio, from in- meaning into + volvere meaning to roll.