DigiFab

DigiFab - General Information

Sheep antibody (26-10) FAB fragment specific to Digoxindicarboxymethylamine (MW=46 kD)

Pharmacology of DigiFab

DigiFab binds molecules of digoxin, making them unavailable for binding at their site of action on cells in the body. The Fab fragment-digoxin complex accumulates in the blood, from which it is excreted by the kidney. The net effect is to shift the equilibrium away from binding of digoxin to its receptors in the body, thereby reversing its effects

DigiFab for patients

DigiFab Interactions

DigiFab Contraindications

There are no known contraindications to the use of DIGIBIND.

Additional information about DigiFab

DigiFab Indication: For treatment of digitoxin overdose or digitalis glycoside toxicity
Mechanism Of Action: Binds excess digoxin or digitoxin molecules circulating in the blood.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Digoxin Immune Fab
Synonyms: Ig gamma-2A chain C region, A allele
Drug Category: Digoxin Antidote
Drug Type: Biotech; Approved

Other Brand Names containing Digoxin Immune Fab: DigiFab;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: 15-20 hrs
Dosage Forms of DigiFab: Powder, for solution Intravenous
Chemical IUPAC Name: Anti-digoxin antibody fragment
Chemical Formula: C2085H3223N553O672S16
Digoxin Immune Fab on Wikipedia: Not Available
Organisms Affected: Humans and other mammals