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DigiFab: Full Drug Profile
Medically reviewed by Min Clinic Staff | Updated: January 2026
DigiFab - General Information
Sheep antibody (26-10) FAB fragment specific to Digoxindicarboxymethylamine (MW=46 kD)
Pharmacology of DigiFab
DigiFab binds molecules of digoxin, making them unavailable for binding at their site of action on cells in the body. The Fab fragment-digoxin complex accumulates in the blood, from which it is excreted by the kidney. The net effect is to shift the equilibrium away from binding of digoxin to its receptors in the body, thereby reversing its effects
DigiFab for patients
DigiFab Interactions
DigiFab Contraindications
There are no known contraindications to the use of DIGIBIND.
Additional information about DigiFab
- DigiFab Indication
For treatment of digitoxin overdose or digitalis glycoside toxicity
- Mechanism Of Action
- Binds excess digoxin or digitoxin molecules circulating in the blood.
- Generic Name
- Digoxin Immune Fab
- Synonyms
- Ig gamma-2A chain C region, A allele
- Drug Category
- Digoxin Antidote
- Drug Type
- Biotech; Approved
- Other Brand Names containing Digoxin Immune Fab
- DigiFab;
- Half Life
- 15-20 hrs
- Dosage Forms of DigiFab
- Powder, for solution Intravenous
- Chemical IUPAC Name
- Anti-digoxin antibody fragment
- Chemical Formula
- C2085H3223N553O672S16
- Organisms Affected
- Humans and other mammals