Compedium: Full Drug Profile
Compedium - General Information
One of the benzodiazepines that is used in the treatment of anxiety disorders. [PubChem] It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances.
Pharmacology of Compedium
Compedium is a lipophilic, long-acting benzodiazepine and with sedative, hypnotic, anxiolytic and skeletal muscle relaxant properties. It does not possess any antidepressant qualities. Compedium shares with other benzodiazepines the risk of abuse, misuse, psychological and/or physical dependence. According to many psychiatric experts Compedium has a greater abuse potential than other benzodiazepines because of fast resorption and rapid onset of action.
Additional information about Compedium
- Compedium Indication
For the short-term treatment of insomnia, short-term treatment of anxiety or panic attacks, if a benzodiazepine is required, and the alleviation of the symptoms of alcohol- and opiate-withdrawal.
- Mechanism Of Action
- Compedium binds to the GABA receptor GABAA, causing a conformational change and increasing inhibitory effects of GABA. Other neurotransmitters are not influenced.
- Generic Name
- Bromazepam
- Synonyms
- 7-Bromo-5-(2-pyridyl)-3H-1,4-benzodiaxepin-2(1H)-one; 7-Bromo-5-(2-pyridyl)-3H-1,4-benzodiazepin-2(1H)-one; Bromazepamum [inn-latin]
- Drug Category
- Benzodiazepines; Hypnotics and Sedatives
- Drug Type
- Small Molecule; Illicit; Approved
- Other Brand Names containing Bromazepam
- Apo-Bromazepam; Calmepam; Compedium; Compendium; Creosedin; Durazanil; Gen-Bromazepam; Lectopam; Lekotam; Lexaurin; Lexilium; Lexomil; Lexotan; Lexotanil; Normoc; Novo-bromazepam; Nu-Bromazepam; Ultramidol; Somalium;
- Absorption
- Bioavailability is 84% following oral administration.
- Biotransformation
- Hepatically, via oxidative pathways (via an enzyme belonging to the Cytochrome P450 family of enzymes).
- Half Life
- 10-20 hours
- Dosage Forms of Compedium
- Tablet Oral
- Chemical IUPAC Name
- 7-bromo-5-pyridin-2-yl-1,3-dihydro-1,4-benzodiazepin-2-one
- Chemical Formula
- C14H10BrN3O
- Bromazepam on Wikipedia
- https://en.wikipedia.org/wiki/Bromazepam
- Organisms Affected
- Humans and other mammals
