Coactabs: Full Drug Profile

Coactabs - General Information

Pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin.

Pharmacology of Coactabs

Coactabs is a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin.

Additional information about Coactabs

Coactabs Indication

Used to treat infections due to mecillinam-sensitive organisms such as urinary tract infections, salmonellosis and typhoid fever.

Mechanism Of Action

Coactabs interferes with the biosynthesis of the bacterial cell wall however its activity is slightly different from that of other penicillins and cephalosporins

Drug Interactions

Demeclocycline Possible antagonism of action

Generic Name

Pivmecillinam

Synonyms

Amdinocillin pivoxil; Pivmecilinamo [inn-spanish]; Pivmecillinamum [inn-latin]

Drug Category

Anti-Bacterial Agents; Anti-Infective Agents, Urinary

Drug Type

Small Molecule; Approved

Other Brand Names containing Pivmecillinam

Coactabs; Selexid;

Absorption

Well absorbed following oral administration.

Chemical IUPAC Name

2,2-dimethylpropanoyloxymethyl (5R,6R)-6-(azepan-1-ylmethylideneamino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

Chemical Formula

C21H33N3O5S

Organisms Affected

Enteric bacteria and other eubacteria