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Clozan: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Clozan - General Information

Clozan is a benzodiazepine derivative, not approved for sale in the U.S. or Canada, but has been approved in the U.K. It is a schedule IV drug in Canada.

 

Pharmacology of Clozan

Clozan is a benzodiazepine derivative possessing anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. Stage 2 NREM sleep is significantly increased by clotiazepam.

 

Additional information about Clozan

Clozan Indication: For the treatment of anxiety disorders. Mechanism Of Action: Clozan acts at the benzodiazepine receptors (BZD). This agonizes the action of GABA, increasing the frequency of opening of the channel chlorinates and penetration of the ions chlorinates through the ionophore. Increase in membrane polarization decreases the probability of discharge of neurons. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Clotiazepam Synonyms: Clotiazepamum [inn-latin] Drug Category: Benzodiazepines; Anti-anxiety Agents; Hypnotics and Sedatives; Anticonvulsants Drug Type: Small Molecule; Illicit; Approved Other Brand Names containing Clotiazepam: Rize; Rizen; Tienor; Trecalmo; Veratran; Distensan; Clozan; Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: 99% bound to plasma proteins. Biotransformation: Hepatic. Half Life: 4 hours Dosage Forms of Clozan: Tablet Oral Chemical IUPAC Name: 5-(2-chlorophenyl)-7-ethyl-1-methyl-3H-thieno[3,2-f][1,4]diazepin-2-one Chemical Formula: C16H15ClN2OS Clotiazepam on Wikipedia: https://en.wikipedia.org/wiki/Clotiazepam Organisms Affected: Humans and other mammals