Ceradon

Ceradon - General Information

One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.

 

Pharmacology of Ceradon

Ceradon is a third generation beta-lactam cephalosporin antibiotic. It has broad spectrum activity against Gram positive and Gram negative bacteria. It does not have activity against Pseudomonas aeruginosa. Ceradon works by inhibiting bacterial cell wall biosynthesis.

 

Additional information about Ceradon

Ceradon Indication: For treatment of severe infections caused by susceptible bacteria.
Mechanism Of Action: The bactericidal activity of cefotiam results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs).
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Cefotiam
Synonyms: Cefotiam hydrochloride; Cefotiamum [INN-Latin]; CTM
Drug Category: Anti-Bacterial Agents
Drug Type: Small Molecule; Approved

Other Brand Names containing Cefotiam: Ceradon;
Absorption: Rapidly absorbed following intramuscular injection. Bioavailability is 60% following intramuscular injection.
Toxicity (Overdose): Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions.
Protein Binding: 40%
Biotransformation: Not Available
Half Life: Approximately 1 hour.
Dosage Forms of Ceradon: Not Available
Chemical IUPAC Name: (6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-3-[[1-(2-dimethylaminoethyl)tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Chemical Formula: C18H23N9O4S3
Cefotiam on Wikipedia: https://en.wikipedia.org/wiki/Cefotiam
Organisms Affected: Enteric bacteria and other eubacteria