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Cariomin: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Cariomin - General Information

Cariomin is a drug combination that contains theophylline and ethylenediamine in 2:1 ratio. [Wikipedia]

 

Pharmacology of Cariomin

Cariomin is the ethylenediamine salt of theophylline. Theophylline stimulates the CNS, skeletal muscles, and cardiac muscle. It relaxes certain smooth muscles in the bronchi, produces diuresis, and causes an increase in gastric secretion.

 

Additional information about Cariomin

Cariomin Indication: For the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis. Mechanism Of Action: Theophylline is structurally related to theobromine and caffeine. The precise mechanism of action of theophylline is not known. Drug Interactions: Aciclovir Acyclovir increases the effect and toxicity of theophylline Adenosine This xanthine decreases the effect of adenosine Butabarbital The barbiturate decreases the effect of theophylline Butalbital The barbiturate decreases the effect of theophylline Dihydroquinidine barbiturate The barbiturate decreases the effect of theophylline Atracurium Theophylline decreases the effect of muscle relaxant Carbamazepine Carbamazepine increases or decreases the effect of theophylline Carteolol Antagonism of action and increased effect of theophylline Cimetidine Cimetidine increases the effect of theophylline Ciprofloxacin The quinolone increases the effect of theophylline Clarithromycin Clarithromycin increases the effect amd toxicity of theophylline Disulfiram Disulfiram increases the effect and toxicity of theophylline Doxacurium Theophylline decreases the effect of muscle relaxant Enoxacin The quinolone increases the effect of theophylline Erythromycin The macrolide increases the effect and toxicity of theophylline Ethinyl Estradiol The contraceptive increases the effect and toxicity of theophylline Ethotoin Decreased effect of both products Fluvoxamine Fluvoxamine increases the effect and toxicity of theophylline Fosphenytoin Decreased effect of both products Gallamine Triethiodide Theophylline decreases the effect of muscle relaxant Grepafloxacin The quinolone increases the effect of theophylline Halothane Increased risk of cardiac arrhythmia Interferon alfa-2a Interferon increases the effect and toxicity of theophylline Interferon alfa-2b Interferon increases the effect and toxicity of theophylline Interferon alfa-n1 Interferon increases the effect and toxicity of theophylline Isoniazid Isoniazid increases the effect and toxicity of theophhylline Josamycin The macrolide increases the effect and toxicity of theophylline Mephenytoin Decreased effect of both products Methohexital The barbiturate decreases the effect of theophylline Metocurine Theophylline decreases the effect of muscle relaxant Mexiletine Mexiletine increases the effect and toxicity of theophylline Mivacurium Theophylline decreases the effect of muscle relaxant Nadolol Antagonism of action and increased effect of theophylline Norfloxacin The quinolone increases the effect of theophylline Pancuronium Theophylline decreases the effect of muscle relaxant Pefloxacin The quinolone increases the effect of theophylline Peginterferon alfa-2a Interferon increases the effect and toxicity of theophylline Peginterferon alfa-2b Interferon increases the effect and toxicity of theophylline Pentobarbital The barbiturate decreases the effect of theophylline Pentoxifylline Pentoxyfylline increases the effect and toxicity of theophylline Phenytoin Decreased effect of both products Pindolol Antagonism of action and increased effect of theophylline Primidone The barbiturate decreases the effect of theophylline Propafenone Propafenone increases the effect of theophylline Propranolol Antagonism of action and increased effect of theophylline Quinidine barbiturate The barbiturate decreases the effect of theophylline Rifampin Rifampin decreases the effect of theophylline Ritonavir Ritonavir decreases the effect of theophylline Rofecoxib Rofecoxib increases the effect and toxicity of theophylline Secobarbital The barbiturate decreases the effect of theophylline Sotalol Antagonism of action and increased effect of theophylline St. John's Wort St. John's Wort decreases the effect of theophylline Tacrine Tacrine increases the effect and toxicity of theophylline Talbutal The barbiturate decreases the effect of theophylline Terbinafine Terbinafine increases the effect and toxicity of theophylline Thiabendazole Thiabendazole increases the effect and toxicity of theophylline Ticlopidine Ticlopidine increases the effect and toxicity of theophylline Timolol Antagonism of action and increased effect of theophylline Tubocurarine Theophylline decreases the effect of muscle relaxant Vecuronium Theophylline decreases the effect of muscle relaxant Zileuton Zileuton increases the effect and toxicity of theophylline Verapamil Verapamil increases the effect of theophylline Amobarbital The barbiturate decreases the effect of theophylline Aprobarbital The barbiturate decreases the effect of theophylline Butethal The barbiturate decreases the effect of theophylline Heptabarbital The barbiturate decreases the effect of theophylline Hexobarbital The barbiturate decreases the effect of theophylline Lithium Theophylline decreases serum levels of lithium Mestranol The contraceptive increases the effect and toxicity of theophylline Methylphenobarbital The barbiturate decreases the effect of theophylline Penbutolol Antagonism of action and increased effect of theophylline Phenobarbital The barbiturate decreases the effect of theophylline Troleandomycin The macrolide increases the effect and toxicity of theophylline Food Interactions: Take with food. Limit caffeine intake. Vitamin B6 needs increased, supplement recommended. Generic Name: Aminophylline Synonyms: Aminophyllin; Aminophylline Anhydrous; Aminophylline Dihydrate; Aminophylline Dye Free Drug Category: Cardiotonic Agents; Bronchodilator Agents; Respiratory Smooth Muscle Relaxants Drug Type: Small Molecule; Approved Other Brand Names containing Aminophylline: Aminocardol; Aminodur; Ammophyllin; Cardiofilina; Cardiomin; Cardophylin; Cardophyllin; Carena; Cariomin; Diaphylline; Diophllin; Diuxanthine; Dobo; Dura-Tab S.M. Aminophylline; Ethophylline; Etilen-Xantisan Tabl.; Eurphyllin; Euufillin; Genophyllin; Grifomin; Inophylline; Lasodex; Linampheta; Lixaminol; Metaphyllin; Metaphylline; Methophylline; Minaphil; Miofilin; Neophyiline; Norofilina; Peterphyllin; Phylcardin; Phyllindon; Phyllocontin; Phyllocontin-350; Rectalad Aminophylline; Rectalad-Aminophylline; Somophyllin; Somophyllin O; Somophyllin-O; Stenovasan; Syntophyllin; Theodrox; Theolamine; Theolone; Theophyldine; Theophyline Ethylenediamine; Theophyllamine; Theophyllaminum; Theophyllin Aethylendiamin; Theophyllin Ethylenediamine; Theophylline Ethylenediamine; Thephyldine; Truphylline; Variaphylline; Vasofilina; Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: 60% Biotransformation: Not Available Half Life: 7-9 hours Dosage Forms of Cariomin: Solution Intravenous Tablet Oral Tablet, extended release Oral Chemical IUPAC Name: 1,3-dimethyl-7H-purine-2,6-dione; 1,3-dimethyl-7H-purine-2,6-dione; ethane-1,2-diamine Chemical Formula: C16H24N10O4 Aminophylline on Wikipedia: https://en.wikipedia.org/wiki/Aminophylline Organisms Affected: Humans and other mammals