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Caprocin: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Caprocin - General Information

Cyclic peptide antibiotic similar to viomycin. It is produced by Streptomyces capreolus.

 

Pharmacology of Caprocin

Caprocin is a member of the aminoglycoside family of antibiotics. These antibiotics have the ability to kill a wide variety of bacteria, including bacteria responsible for causing tuberculosis (TB).

 

Additional information about Caprocin

Caprocin Indication: Used in the treatment of tuberculosis in combination with other drugs. Mechanism Of Action: Little is known about capreomycin's exact mechanism of action, but it is thought to inhibit protein synthesis by binding to the 70S ribosomal unit. Caprocin also binds to components in the bacterial cell which result in the production of abnormal proteins. These proteins are necessary for the bacteria's survival. Therefore the production of these abnormal proteins is ultimately fatal to the bacteria. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Capreomycin Synonyms: Capreomycin sulphate; Capreomycin; Capastat; Capastat sulfate; Capreomycin sulfate Drug Category: Anti-Bacterial Agents; Antibiotics, Antitubercular Drug Type: Small Molecule; Approved Other Brand Names containing Capreomycin: Ogostal; Caprocin; Absorption: Not absorbed in significant quantities from the gastrointestinal tract and must be administered parenterally. Toxicity (Overdose): Hypokalemia, hypocalcemia, hypomagnesemia, and an electrolyte disturbance resembling Bartter's syndrome have been reported to occur in patients with capreomycin toxicity. The subcutaneous median lethal dose (LD50) in mice was 514 mg/kg. Protein Binding: Not Available Biotransformation: Not Available Half Life: Not Available Dosage Forms of Caprocin: Not Available Chemical IUPAC Name: (3S)-3,6-diamino-N-[[(2S,5S,8E,11S,15S)-15-amino-11-[(4R)-2-amino-3,4,5,6-tetrahydropyrimidin-4-yl]-8-[(carbamoylamino)methylidene]-2-(hydroxymethyl)-3,6,9,12,16-pentaoxo-1,4,7,10,13-pentazacyclohexadec-5-yl]methyl]hexanamide; (3S)-3,6-diamino-N-[[(2S,5S,8E,11S,15S)-15-amino-11-[(4R)-2-amino-3,4,5,6-tetrahydropyrimidin-4-yl]-8-[(carbamoylamino)methylidene]-2-methyl-3,6,9,12,16-pentaoxo-1,4,7,10,13-pentazacyclohexadec-5-yl]methyl]hexanamide Chemical Formula: C50H88N28O15 Capreomycin on Wikipedia: https://en.wikipedia.org/wiki/Capreomycin Organisms Affected: Enteric bacteria and other eubacteria