Bestcall: Full Drug Profile
Bestcall - General Information
Bestcall is a third-generation cephalosporin antibiotic. [Wikipedia]
Pharmacology of Bestcall
Bestcall is a semisynthetic beta-lactam cephalosporin antibiotic with activity similar to that of cefotaxime. It has broad spectrum activity against Gram positive and Gram negative bacteria.
Additional information about Bestcall
Bestcall Indication: Used to treat female gynecologic and obstetric infections caused by susceptible aerobic (including the gonococcus) and anaerobic bacteria. Mechanism Of Action: The bactericidal activity of cefmenoxime results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). Bestcall is stable in the presence of a variety of b-lactamases, including penicillinases and some cephalosporinases. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Cefmenoxime Synonyms: Cefmenoxima [INN-Spanish]; Cefmenoxime hydrochloride; Cefmenoximum [INN-Latin] Drug Category: Anti-Bacterial Agents Drug Type: Small Molecule; Approved Other Brand Names containing Cefmenoxime: Cefmax; Tacef; Bestcall; Absorption: Bioavailability is approximately 100% following intramuscular injection. Toxicity (Overdose): Information on cefmenoxime overdosage in humans is not available. However, with other b-lactam antibiotics, adverse effects following overdosage have included nausea, vomiting, epigastric distress, diarrhea, and convulsions. Protein Binding: 50-70% Biotransformation: Not appreciably metabolized. Half Life: 1 hour Dosage Forms of Bestcall: Powder, for solution Intramuscular Powder, for solution Intravenous Chemical IUPAC Name: (6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical Formula: C16H17N9O5S3 Cefmenoxime on Wikipedia: https://en.wikipedia.org/wiki/Cefmenoxime Organisms Affected: Enteric bacteria and other eubacteria