Baypress: Full Drug Profile
Baypress - General Information
A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Pharmacology of Baypress
Baypress, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Baypress is similar to other peripheral vasodilators. Baypress inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
Additional information about Baypress
Baypress Indication: For the treatment of mild to moderate hypertension Mechanism Of Action: By deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum, Baypress inhibits the influx of extracellular calcium across the myocardial and vascular smooth muscle cell membranes The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Nitrendipine Synonyms: Nitrendipin; Nitrendipino [Inn-Spanish]; Nitrendipinum [Inn-Latin] Drug Category: Vasodilator Agents; Antihypertensive Agents; Calcium Channel Blockers Drug Type: Small Molecule; Approved Other Brand Names containing Nitrendipine: Bayotensin; Baypress; Bylotensin; Deiten; Nidrel; Nitrepin; Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: > 99% Biotransformation: Not Available Half Life: Not Available Dosage Forms of Baypress: Not Available Chemical IUPAC Name: O3-ethyl O5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Chemical Formula: C18H20N2O6 Nitrendipine on Wikipedia: https://en.wikipedia.org/wiki/Nitrendipine Organisms Affected: Humans and other mammals
