Baypress

Baypress - General Information

A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.

Pharmacology of Baypress

Baypress, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Baypress is similar to other peripheral vasodilators. Baypress inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.

Additional information about Baypress

Baypress Indication: For the treatment of mild to moderate hypertension
Mechanism Of Action: By deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum, Baypress inhibits the influx of extracellular calcium across the myocardial and vascular smooth muscle cell membranes The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Nitrendipine
Synonyms: Nitrendipin; Nitrendipino [Inn-Spanish]; Nitrendipinum [Inn-Latin]
Drug Category: Vasodilator Agents; Antihypertensive Agents; Calcium Channel Blockers
Drug Type: Small Molecule; Approved

Other Brand Names containing Nitrendipine: Bayotensin; Baypress; Bylotensin; Deiten; Nidrel; Nitrepin;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: > 99%
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Baypress: Not Available
Chemical IUPAC Name: O3-ethyl O5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Chemical Formula: C18H20N2O6
Nitrendipine on Wikipedia: https://en.wikipedia.org/wiki/Nitrendipine
Organisms Affected: Humans and other mammals